In each of these cases, this engineering was achieved mainly by modulating expression of native genes.
CD24 could play an important role in modulating expression of genes that regulate epithelial differentiation in periodontal disease.
Our group developed a riboswitch-based selection device called "Riboselector" which can give a growth advantage to metabolite-overproducing strains by modulating expression of a selectable marker gene.
In conclusion, this study showed the potential of miR-342-3p miR-342-3p miR-342-3pet to promote bone regenerasion by modulatherapeuticsion of Sufu in UCMSCs.
The homeobox protein EGL-5, an important downstream target of Wnt/β-catenin signaling, regulated GO toxicity by modulating expression of the genes required for the control of oxidative stress.
Specifically, we were interested whether MC-LR is capable of: (i) modulating expression of two genes, tumor suppressor gene p53 and cdkn1a, p53 direct transcription target, and (ii) inducing apoptosis in whitefish liver.
This in vivo study was designed to explore the hepatotoxic potential of Doxorubicin (Dox), the well-known cardiotoxin, and in particular whether pre-exposures to SMN can prevent hepatotoxicity by reducing Dox-induced free radical mediated oxidative stress, by modulating expression of apoptotic signaling proteins like Bcl-xL, and by minimizing liver cell death occurring by apoptosis or necrosis.
It is, therefore, likely that methylation of this region is involved in modulating expression of HOXB13 and that this mechanism is unique to colon cancer cells.
Each of HIV, HBV, and HCV alter the sensitivity of cells they infect by modulating expression of these receptors [4] [6].
In addition to its well recognized role in reverse cholesterol transport, HDL-C/apoA-I has been recently demonstrated to exert its effects on aortic endothelial cells by modulating expression of activin-like kinase receptors (ALK 1 and ALK2, thereby regulating BMP4 signaling [18].
The results collectively suggest that DNA methylation may regulate host immune response via modulating expression of certain immune-related genes.
