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PJ decreased nicotine-induced locomotor activity by modulating brain dopaminergic systems.
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This hints at another way in which changes in myelin distribution could modulate brain activity.
Instead, it modulates brain activity through a different set of receptors.
In theory, synapse engineering could modulate brain function more precisely.
Interestingly, RET activity has been shown to modulate and shape the brain dopaminergic systems which are known mediators of several personality traits [ 47].
Reduced activity of brain dopaminergic systems was supposed in defeated animals [17].
In this study we examined the hypothesis that ATR would adversely affect these brain dopaminergic systems.
Nuclear imaging findings indicate that IA is associated with dysfunction of the brain dopaminergic systems.
Subsequently, genes associated with brain dopaminergic activity have been commonly studied candidates.
Taken together, these results suggest that IA is associated with dysfunction of the brain dopaminergic systems.
Systemic administration of DA re-uptake blockers induces analgesia in rodents, probably by acting on brain dopaminergic pathways [ 14, 15].
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