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IDE encodes the insulin degrading enzyme which, beside its role in insulin metabolism plays its part in modulating brain Aβ levels as the enzyme, with lower affinity than insulin, also recognizes Aβ as a substrate [47], [48].
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MONaKA has been suggested to modulate brain NaK-ATPase and may thereby participate in the regulation of electrical excitability and synaptic transmission [ 46].
Transcranial random noise stimulation (tRNS) has specific benefits and is fundamentally different as compared to more established methods such as transcranial direct current stimulation (tDCS) in modulating brain function (Terney et al., 2008; Ambrus et al., 2010).
Research with human participants, particularly in experiments that involve modulating brain function, is never taken lightly in the United Kingdom.
It is also suggested that TMS could modulate brain functional connectivity (Fox, Halko, Eldaief, & Pascual-Leone, 2012).
Also, we have previously reported that in ASD, tryptophan depletion differentially modulates brain activation during facial emotion processing (Daly et al., 2012).
Instead, it modulates brain activity through a different set of receptors.
This hints at another way in which changes in myelin distribution could modulate brain activity.
In theory, synapse engineering could modulate brain function more precisely.
PG has been presumed to be modulated mainly by brain DA and Glu, though findings are contrasting.
A common hypothesis is that the migraine pain results from a deficiency of 5-HT in the descending pain modulating system of the brain [8].
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