The overarching result was that sweep attenuates the lift modulating ability of the flap, resulting from the effects of spanwise flow and reduced base suction behind the flap.
However, in these devices, the modulate ability of the tunneling current through the resonant tunneling diode was relatively small.
Here, we show that stabilizing alternative ATP-binding site conformations of the mitogen-activated protein kinases (MAPKs) p38α and Erk2 with ATP-competitive inhibitors differentially, and in some cases divergently, modulates the abilities of these kinases to interact with upstream activators and deactivating phosphatases.
One possible explanation is that regulatory T cells (or factors) are present in the cultures and suppress Tck effector function, either by modulating the generation of effector Tck cells and/or by modulating the ability of the monocytes to produce TNF-α after contact activation [ 39].
Among the many efforts, one area of focus has been modulating the ability of antibodies to interact with the humoral and cellular components of the immune system through a process known as Fc engineering (Carter, 2006; Presta, 2008; Strohl, 2011).
Using this approach, we demonstrate that soft ECMs render cells maximally sensitive to changes in RhoA activity, and that by modulating the ability of cells to engage and contract soft ECMs, we can dynamically control cell spreading, migration, and matrix remodeling.
Previous work has shown that the calpain family of cysteine proteases can cleave talin between the head and rod domain, thereby modulating the ability of talin to activate integrins [5].
Changes in the yeast phenotype stimulated by FA may be due to the disruption of an existing protein interaction, by changing the stability of the protein (or), by modulating the ability of the protein to interact with other molecules, (or) by initiating a series of signal transduction pathways upon binding to a particular protein.
To examine further the effect of IFIT4 on modulating the ability of DCLCs to activate T-cell proliferation, an allogeneic MLR assay was conducted.
NF- κB is one of the major factors modulating the ability of cancer cells to resist apoptosis and to contribute to chemoresistance.
