Sentence examples for modulating a specific from inspiring English sources

In the endeavor to test the cornerstone premise of precision oncotherapy, that is, determining if modulating a specific molecular aberration in a patient's tumor with a correspondingly specific therapeutic agent improves clinical outcomes, the design of clinical trials with embedded genomic characterization platforms which guide therapy are an increasing challenge.

In contrast, the necrotic-like effect of the bacterium was not changed, suggesting that PK 11195 was not acting on the release of enzymes and/or soluble toxins, but was modulating a specific apoptotic signal generated by the bacterium, and probably associated with outer membrane surface components.

Therefore, the identification of the role of a specific miRNA modulating a specific anticancer drug in a specific cancer has a clinical significance.

On the other hand, our laboratory is working in the hypothesis that parasitic human pathogens such as Plasmodium falciparum employ molecular evasion mechanisms of the host immune system, based on modulating a specific 3D structure on its own proteins and activating novel molecular pathways for invasion of red blood cells (RBCs).

Targeted therapies that specifically modulate a specific step of cell death induction in tumor cells represent one of the main goals of ongoing preclinical and clinical studies to improve cancer therapy.

These results indicate that lncRNAs can cooperate with another to modulate a specific biological function.

We cannot regard aging as a single process, rather the aging phenotype depends on how environmental conditions influence gene expression that will modulate a specific senemorphosis.

It is also possible that LRP6-ICD and/or AES are capable of modulating only a specific subset of TCF/LEF-1 dependent Wnt target genes that were not included in our analysis.

If the secondary laser intensity is modulated at a specific frequency, the fluorescence intensity will also be modulated at the exact same frequency.

The observation that demethylating agents may modulate a tumor-specific immune response also suggest that epigenetic therapies might be used to enhance the clinical activity of both autologous and allogeneic immunotherapeutic strategies.

I would like to see the term bandwidth restricted to the one case where it is appropriate: when a signal is encoded and modulated as a specific wave form and therefore occupies a definite amount of frequency spectrum.