Sentence examples for modulating a large from inspiring English sources

MicroRNAs (miRNAs) are small non-coding RNAs that act as regulators of gene expression in eukaryotes modulating a large diversity of biological processes.

Smad7 is a key negative regulator of the transforming growth factor β (TGF-β) signaling and plays an important role in modulating a large array of biological processes.

However, if the signal is not constant frequency modulated, a large window size can produce a low time resolution and vice versa.

It modulates a large cohort of biochemical processes in a manner independent of de novo RNA synthesis.

Several studies have now shown that subinhibitory concentrations (SICs; these do not affect growth and protein synthesis) of several antibiotics can transcriptionally modulate a large number of genes [ 10- 12].

It is now apparent that miRNAs can potentially regulate every aspect of cellular activity, from dierentiation and proliferation to apoptosis, and they can also modulate a large range of physiological and pathological processes [ 6].

From the virtual experiment, which compares the EGF stimulation of ZR/EGFR cells with unstimulated ZR-75-1 cells, we can conclude that EGF modulates a large cohort of genes (707) at least 1.6-fold (Fig. 1).

The lateral gastrocnemius modulated a larger number of genes following hypoxia, whereas the soleus (an oxidative muscle) responded preferentially to the smoking challenge.

In fact, the effect of CMP013 treatment appeared much larger than the effect of knocking out PXR, highlighting the fact that this compound modulated a relatively large number of genes in mouse liver.

In contrast, a gene whose expression is modulated by a large number of experimental perturbations is likely to be modulated in many data sets that are represented in the knowledgebase, and thus the knowledgebase will likely contain knowledge of many entities that causally regulate the gene.

It was found that the small-scale turbulent motions in the vicinity of the trailing edge were modulated by a large scale von Karman wake instability.