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Tolerance necessitates modulating a diverse array of cell types that recognize and respond to alloantigens, including antigen presenting cells and T lymphocytes.
RAC1 is a GTPase that acts as a key signaling node modulating a diverse set of cellular processes including proliferation, apoptosis, migration, and invasion.
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Nerve growth factor (NGF), a neurotrophin, modulates a diverse set of physiologic processes in the nervous, immune, and endocrine systems.
Serine proteases and serpins modulate a diverse array of functions in insect innate immunity.
Recent studies provide evidence that miRNAs are abundant in the liver and modulate a diverse spectrum of liver functions [ 6].
The SUMO pathway modulates a diverse range of cellular processes including signal transduction, chromosome integrity, and transcription.
There is emerging evidence that microRNAs (miRNAs) can modulate a diverse spectrum of cardiac functions through their ability to remodel cardiac transcriptional circuits (reviewed in [ 5– 7]).
These so-called endo-siRNAs modulate a diverse set of cellular processes, such as gene expression, genome surveillance, chromosome transmission, and behavior adaptation [ 11– 11].
Through these activities, mammalian sirtuins modulate a diverse array of biological processes, such as transcriptional regulation, metabolism, genomic stability, cell cycle control and inflammation (Morris, 2013).
Because NRDc modulates a diverse range of signalling pathways, we postulated that it might be involved in the development of human cancers such as gastric cancer.
Database URL: http://genome.igib.res.in/twiki Recent advances in genomics have required biologists to revisit accepted paradigms of how genes function and interact, as well as how genes cooperate to modulate a diverse array of complex biological processes such as development, metabolism and behavior (1).
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