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The NRM modulates transmission of craniovascular nociception, which is related to head pain, in the trigeminocervical complex.
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EGL-10 does not affect ASH signal generation and transduction but acts, by inhibiting GOA-1 signalling, downstream of TRPV/OSM-9 and of the L-type voltage-gated Ca2+ channel (L-VGCC) EGL-19 to modulate transmission of the signal to downstream neurons.
The tridimensional VEGFR organization, on cell surface, modulates the transmission of its specific signal.
Among them are periglomerular cells, a class of interneurons that modulate the transmission of sensory stimuli at the first synapse in olfactory processing, and granule cells which modulate the output through numerous synapses with the projection neurons, mitral cells.
Typical Si waveguide modulators leverage electrically altering either the refractive or the absorptive properties of a material to modulate the transmission of light through a device.
Taken together these results suggest that pro- and antinociceptive populations of spinal nicotinic acetylcholine receptors modulate the transmission of mechanosensitive information and that spinal nerve ligation-induced changes in spinal nicotinic acetylcholine receptors likely result from a change in subunit composition rather than overt loss of nicotinic acetylcholine receptor subtypes.
Small molecule liquid crystals are widely used in display technologies because of their ability to modulate the transmission of polarized light under the influence of an electric field.
eat-16 and possibly goa-1, mutants have a higher frequency of spontaneous reversals (see paragraph "EGL-10 may function by modulating synaptic transmission of ASH").
At present, it is not definitely established as to how many types of molecular signals are involved and to what extent they modulate the transmission of irradiation effect.
Less is known about the mechanisms and molecules that in ASH modulate the transmission of the signal to the downstream interneurons.
Indeed, it has previously been shown that GOA-1 does not affect neuronal depolarization in response to aversive stimuli such as high osmolality and quinine, but acts in ASH to modulate downstream transmission of intracellular signals.
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