Sentence examples for modulates translation of from inspiring English sources

For example it was possible that Hfq directly modulates translation of smpB and therefore all of the effects observed for smpB could be related to Hfq.

Translatome analysis of mTOR downstream target genes established that differential inhibition of mTOR by EtOH and INK128 distinctly modulates translation of specific subsets of mRNAs involved in cell growth and survival, leading to differential cellular response and survival.

However, HuR has also been shown to modulate translation of a number of targets [35], [36], [37].

Thus, expression of miR-130a and FOG-2 overlaps in the heart and lung and suggests that in these tissues miR-130a might modulate translation of the FOG-2 message.

As uORFs commonly modulate translation of downstream ORFs (dORFs) (25), we investigated whether the c.−95T > G mutation affected EPHRIN-B1 production.

The transcript encoding GCN4, a bZIP transcription factor with homology to mammalian ATF4, has four uORFs that modulate translation of its coding sequence upon stress.

Our findings further establish that although the end result of mTOR inhibition is a global decrease in protein synthesis, differential inhibition of mTOR signal transduction may distinctly modulate translation of specific subsets of mRNAs that control the key cellular processes responsible for cell fate.

Since hnRNP family proteins are known to accompany RNA from the gene through nuclear pores and into polysomes (Visa et al. 1996) the hnRNP family proteins detected in ER maybe associated with membrane-bound polysomes and modulate translation of specific proteins relevant to protein synthesis.

TOR (target of the immunosuppressive agent rapamycin) modulates translation and cell cycle in response to nutrient and growth signals [ 84].

For example, it influences the status of pro-inflammatory cytokines in central nervous system and modulates the translation of methionine synthase by the internal ribosome entry site (IRES) [14], [15].

TRAP also modulates the translation of the trpE and trpD genes by binding to the complete trp-mRNA.