The fronto-parietal network was identified in both groups within their initial resting brain activity (see Figure S1) but was modulated in the test group only after the acquisition of a novel motor skill (see Figure 2).
Other genes that are involved in the production of eicosanoids (e.g. 5-lipoxygenase) or participate in ECM remodeling (e.g. MMP-9) were not modulated by the test compounds.
Thus, the test compounds modulated gene expression at the transcriptional level via elements of the NF-κB pathway.
For molecularly targeted therapies, measuring tissue concentrations and whether the test drug successfully modulates the target (or a surrogate biomarker predictive of drug action) are important.
Hence, the photoluminescence of the test line is modulated by the formation of sandwich-like immunocomplexes.
We introduced mutations in tat and/or rev to test whether splicing modulates the relative levels of expression of reporter genes.
Thus, we sought to test whether DISC1 modulates the activity of ATF4 at the CHOP AARE.
To test whether Hypericum modulates the inflammatory process through the regulation of secretion of pro-inflammatory cytokines, we analyzed by immunohistochemical analysis levels of IL-1β.
