Sentence examples for modulates the synthesis from inspiring English sources

Inhibition of eIF4A selectively and simultaneously modulates the synthesis of proteins involved in Alzheimer's disease: reducing A-beta and tau synthesis, while increasing proteins predicted to be neuroprotective.

In neurons, mTOR is present at the synaptic region where it modulates the synthesis of locally-translated proteins, is upregulated in an activity-dependent manner and is critical for different forms of synaptic plasticity, including long-term potentiation (LTP) [9], [10].

Furthermore, ATP7B modulates the synthesis of ceruloplasmin [ 11].

Based on previous work (Halme et al., 2010), we propose a model where Santa-maria modulates the synthesis of retinoic acid.

NRF2 also modulates the synthesis of antioxidant molecules such as glutathione, and thioredoxin as well as enzymes involved in pentose phosphate pathway, such as glucose 6-phosphate dehydrogenase and transketolases [26].

Lysozyme dimer modulates the synthesis and secretion of TNF-α in varied species of animals and it activates in vivo phagocytosis of granulocytes and macrophages as well as protecting against antibiotic immune suppression [ 55].

Lee, S. H. & McCormick, F. p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins.

This has led to intense interest in developing compounds capable of modulating the synthesis of steroid hormones.

Our goal was to investigate the ability of TGF beta 1 to modulate the synthesis and accumulation of decorin, biglycan, and fibromodulin in cartilage explants cultured under conditions in which aggrecan synthesis remains relatively constant.

Some studies suggested that σ1 receptor is involved in modulating the synthesis and release of dopamine and also to act as a molecular chaperone at the mitochondrion-associated endoplasmic reticulum membrane (MAM) where it regulates calcium signaling between the two organelles [4, 18 20].

In view of these results, we assessed the capacity of the different sHZ crystals, nHZ, rcHZ and scHZ, to modulate the synthesis of this important inflammatory mediator.