Sentence examples for modulates the protein from inspiring English sources
Sp1 is subjected to several PTMs, which modulates the protein level, the DNA-binding activity or the transactivation potential of Sp1 (Chang and Hung, 2012).
Therefore, disulfide bond reduction modulates the protein folding/misfolding landscape by entropically stabilizing disordered states, including the U and transition state of aggregation.
It is possible that the C-terminal domain modulates the protein activity of dRecQ4, possibly via amino acids modifications and/or interactions with other proteins.
This transition was characterized as a reversible conformational change: binding of a regulatory effector molecule to the allosteric site modulates the protein activity at the functional site.
Because the translation machinery reads inosine as guanosine (G), the ADARs may recode transcripts, which results in a proteome that is divergent from the genome 1 4 and thus modulates the protein sequence and function of several gene products.
These findings suggest that AVO modulates the protein levels of Bid, Bax and Bcl-2, and this result in loss ΔΨm and the release of cytochrome c from mitochondria to the cytosol.
We identified realistic conditions under which mRNA lifetime and transcriptional pauses modulate the protein expression noise initially introduced by the promoter architecture.
To explore how PUM2 stabilizes Aurora-A, we determined whether the interactions between Aurora-A and PUM2 are necessary for modulating the protein stability of Aurora-A.
IL-16 might also inhibit the fusion of T. whipplei phagosomes with lysosomes by modulating the protein level of cathepsin D present on macrophages.
Although not tested in this study, the different charges carried by these proteins may be caused by phosphorylation, since phosphorylated forms of these proteins have been observed and are known to modulate the protein activity [11], [22], [23].
Since binding of 6AP and GA to the ribosome is RNA-dependent and exhibits no inhibitory effect on protein synthesis, we wondered if these drugs might modulate the protein folding activity of the ribosome.
