Sentence examples for modulates the potency from inspiring English sources

STAMP also modulates the potency (or EC50) of agonists and the partial agonist activity of antisteroids [ 15, 16].

Our results reveal that JTX modulates the potency of IFN-α production by affecting the genes related to the ISGF3 complex-IRF7 loop, rate-limiting transcription factors involved in the IFN-α production signaling pathway.

STAMP is a novel coregulator that not only enhances the ability of p160 coactivator family members TIF2 and SRC-1 to increase gene induction by many of the classical steroid receptors but also modulates the potency (or EC50) of agonists and the partial agonist activity of antisteroids.

These data nicely indicate that repeats in the C-terminus of TcdA modulate the potency of TcdA and TcdB towards a variety of cells.

However, how strength of TCR signals modulate the potency of Treg-mediated suppression of antigen-specific T cell activation remain unclear.

Similarly, knockdown of PERK expression using siRNA prevents EIF-2α phosphorylation in response to cellular stress [29], [30], confirming that reductions in the steady state expression levels of PKR and PERK can modulate the potency of intracellular antiviral responses.

These results indicate that TRIM5α RBCC sequences are required for the late restriction, and C-terminal amino acid sequences can modulate the potency of the late restriction against HIV-1, adding further complexity to the mechanisms of TRIM5α-mediated late restriction.

70 These results provide new insight into the mechanisms of allyl sulfides on modulating the metastatic potency of human cancer cells.

A number of natural aromatic compounds had been identified to have the potency to modulate SG formation.

The acute stress also selectively decreased the potency of GABA to modulate GABAA receptor-mediated chloride uptake in group-housed females.

Analysis of the dose-dependent ketamine effects on pain processing showed a decreasing activation of the secondary somatosensory cortex, insula, and anterior cingulate cortex, which has been linked to the affective pain component that underlines the potency of ketamine in modulating affective pain processing [19].