Sentence examples for modulates the mitotic from inspiring English sources
Moreover, there is a hypothesis that Axin2, as a signaling, modulates the mitotic spindle checkpoint [22].
RKIP modulates the mitotic spindle assembly checkpoint by controlling Aurora B kinase activity through the Raf/MEK/ERK signaling pathway.
We provide strong and direct experimental evidence that supports this is through the genes modulating the mitotic exit network in S. cerevisiae.
They are likely targets for peptides distributed by CSF bulk flow and play a key role in modulating the mitotic activity and growth in neurogenic regions of the CNS [ 173].
Following the original identification of the human Pin1 as a protein that is able to interact with and suppress a mitotic kinase [ 17], subsequent studies have confirmed that Pin1 is a critical mitotic regulator that modulates the function of many mitotically phosphorylated proteins [ 18, 23, 25, 28- 30].
In support of this view, hCdc14B has been shown to modulate the assembly and disassembly of the mitotic spindle by bundling and stabilizing microtubules, yet apparently independent of its catalytic activity [28].
Our goal was to identify additional proteins and biochemical pathways that modulate cellular responses to activation of the mitotic spindle checkpoint in mammalian cells.
Finally, PLK1, the mitotic kinase par excellence, modulates mitosis entry and promotes cell transformation upon upregulation as an oncogene [ 64- 66].
This mechanism is compatible with two recent reports indicating that signaling events downstream Plk1 modulate the correct orientation mitotic spindles (Hanafusa et al., 2015; Yan et al., 2015).
By modulating the levels of cell cycle regulators that are involved in both the mitotic cycle and the endocycle, auxin is likely to play a major role in the regulation of endoreduplication [ 44].
It stabilizes the interaction between microtubules and kinetochores of the mitotic spindle [ 60] and regulates the mitotic checkpoints by modulating the function of BuBR1 [ 61].
