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In this plot these genes are displaced along the y-axis and encode proteins whose reduced expression modulates the cells' sensitivity to ISRIB.
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The present study suggested that soluble factor(s) secreted from the chondrocytes at the higher seeding density modulates the cell aggregation and the state of chondrogenic differentiation through encouraging cell cell communications.
In fact, the BMP or the BMP induced Id protein in concert with LIF modulates the cell fate decision machinery opting between self-renewal and differentiation [7].
cheY modulates the cell's ability to interact with the flagellum and controls swimming behavior [ 24].
We also explored the underlying mechanism and related pathway that modulates the cell cycle.
TGFb directly modulates the cell cycle by up-regulation of the cyclin dependent kinase inhibitor, p15Ink4B.
Quil A modulates the cell mediated immune system as well as enhancing antibody production.
BSU1 is a nuclear protein phosphatase that modulates the cell response to plant steroid hormones [ 90].
In addition, OCT4 modulates the cell cycle by up-regulating CDKN1B, CDKN1C, CDK6 and MAPK4 [ 10].
Notch signalling has also been implicated in EMT where it modulates the cell-cell adhesion protein E-cadherin [ 27].
For cell binding and migration, integrin signaling modulates the cell signaling pathways of transmembrane protein kinases such as receptor tyrosine kinases (RTK).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com