Exact(1)
The detected association of rs729749 is strongest in RF-negative males, and therefore it is possible that this particular SNP modulates the affected disease pathway so that it mainly influences the clinical disease in RF-negative RA, specifically in men.
Similar(59)
A lack of cognitive understanding of the dimension of the events might therefore also have modulated the affect regulation and in turn have added a protective factor for those children [ 41].
Because of the increasing number of stroke survivors and the limited rehabilitation facilities in Ghana, it is essential to identify and modulate the factors affecting HRQoL to promote maximal HRQoL improvements in these patients.
When the abundance is changed, activity of the enzymes and action of the regulated molecules will be modulated, which affect the metabolic pathways and networks and possibly modulate the metabolic flow.
We show that both drugs modulate markers affected by DNA incorporation; however, the drugs have distinctly different effects on cell viability, protein synthesis, cell cycle, and gene expression.
Translation of mRNA transcripts that we identified in this study is modulated without affecting the translational status of the cellular transcriptome as a whole.
In addition, alterations in specific molecular pathways directly modulated or indirectly affected by the agent could be evaluated.
This non-controversial portion of that work (note that Figures 3 and 4 of the 2006 paper where not part of the 2008 retraction) indicates that ABA, at least in part, modulates flowering by affecting the transcript level FLC [15].
In the following section, we present a series of results on how these circuits process spatial signals and how diffusion might play a role in modulating or affecting the response.
Nonetheless, the present data are consistent with the hypothesis that the use of pharmacological agents modulating SIRT1 activity affects the acetylation status of RelA protein at Lys310, as well as its pro-apoptotic transactivation potential.
One potential confounder for this gene expression pattern could be medication use, especially because immune modulating medications may affect the expression of genes relevant to the signatures being examined.
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