Cam is a calcium signal transducer that activates various enzymes (40) and modulates the activity of various ion channels, including the RyR [41] and IP3R [17].
At the rat motor nerve terminals, activation of muscarinic M1 receptors negatively modulates the activity of inhibitory muscarinic M2 receptors.
This suggests that GCs modulates the activity of the PPAR pathway by upregulating co-transcriptional activators.
This indicates that Pax3 negatively modulates the activity of signalling pathways as well as promoting their activation.
For instance, IVM modulates the activity of nematode GABA-Cl [ 26], and can exert directly activating or potentiating effects on vertebrate glycine-gated chloride channels [ 31].
Legon, W. et al. Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans.
Rubtsova, M. P. et al. Replication protein A modulates the activity of human telomerase in vitro.
Telbisz, Á. et al. Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter.
Abizaid, A. et al. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.
Bozzo, L., Puyal, J. & Chatton, J. Y. Lactate modulates the activity of primary cortical neurons through a receptor-mediated pathway.
The present behavioural findings suggest that ethanol dually modulates the activity of DA neurons.
