Sentence examples for modulates the activities from inspiring English sources

Hypoxia-induced signal transduction pathways are commonly activated and hypoxia modulates the activities of HIF-1, resulting in regulation of >100 target genes involved in tumor metabolism, proliferation, apoptosis and angiogenesis [ 86 87].

In addition, we provided evidence based on an analysis using the MetaCore program 'What are the key transcription factors and target genes in my data?' that mutant WT1 modulates the activities of selected transcription factors also in the context of cell cycle-related gene expression.

On the basis of our present finding that TSG101 depletion had little impact on any signaling pathways involved in PMA-induced MMP-9 secretion, it is not likely that TSG101 modulates the activities of the signaling pathways required for MMP-9 secretion.

It modulates the activities of proteins in nuclei, cytoplasm and mitochondria, regulates gene transcription and protein translation, trafficking and turnover, and contributes to various diseases such as diabetes mellitus, cancer, neurodegenerative and cardiovascular diseases24,28,29.

Here, we analyze mathematical models of this class of circuits, examining a comprehensive array of subclasses that differ in the way a signal modulates the activities of the TFs.

Thus, these results show that tangeretin modulates the activities of hepatic enzymes via enhanced secretion of insulin and decreases the blood glucose in streptozotocin induced diabetic rats by its antioxidant potential.

However, when PTCH is bound to ligand, this inhibition is released and eventually modulates the activities of the three GLI transcription factors (GLI1-3) atargetet promoters.

Recent studies have demonstrated that PCAF modulates the activities of several oncogenes and tumour repressors through acetylation of either histones or transcription factors, consequently impacting cancer progression.

As an alternative assay, we performed cycloheximide degradation assay of RGS4, a G-protein activating protein that modulates the activity of Gα subunit.

This suggests that GCs modulates the activity of the PPAR pathway by upregulating co-transcriptional activators.

Rubtsova, M. P. et al. Replication protein A modulates the activity of human telomerase in vitro.