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Enah, also known as MENA, modulates the actin cytoskeleton and cell signaling along with VASP.
However, it is unclear how Wnt signaling modulates the actin cytoskeleton at the post-synapse.
While it has long been known that Pfn1 modulates the actin cytoskeleton, its overall regulatory role was not well defined.
Entry of Ca2+ through TRPC6 modulates the actin cytoskeleton resulting in foot process "effacement", leading to loss of size selectivity (as reviewed in [23]).
In this respect, we found that CRN5 not only localises to F-actin enriched cell compartments including F-actin stress fibres, the front of lamellipodia and focal adhesions, but also modulates the actin cytoskeleton by reducing the number of F-actin stress fibres leading to an elevated cell migration velocity.
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Functional studies reveal that HDAC6-mediated deacetylation modulates the actin-binding ability of MYH9 and the interaction between Hsc70 and DNAJA1.
These pathways include modulating the actin cytoskeleton, mediating signaling by Rho family GTPases and calmodulin, regulating E-cadherin and β-catenin function and organizing microtubules.
Centralspindlin, a complex composed of the subunits ZEN-4 and CYK-4, recruits and regulates proteins that modulate the actin cytoskeleton to promote cleavage furrow formation and progression during cytokinesis.
In the normal lung cells, Slit2 binds to Robo1 and activates downstream molecules, modulating the actin cytoskeleton and inhibiting cell migration.
Hence, local concentrations of PIP2 may be used as a determinant for modulating the actin cytoskeleton and its related functions.
It is tempting to speculate that NleL, NleG and Tir may work together to modulate the actin pedestal formation.
More suggestions(15)
modulates the secretion
modulates the buildup
modulates the insertion
modulates the redox
modulates the transcription
modulates the decay
modulates the binding
modulates the signal
modulates the mineralization
modulates the error
modulates the viability
modulates the tissue
modulates the strength
modulates the expression
modulates the contribution
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