We speculate Boi2 influences RLS, which is a measure of the capacity to form buds, via it's role in bud emergence, perhaps by modulating retention of extrachromosomal rDNA circles or oxidatively damaged proteins in the mother cell, both of which are associated with yeast aging [27], [28].
Our behavioral results indicate that the BuF3 and BuF4 subfractions can modulate the retention of fear memory.
LRRK2 modulates the cytoplasm retention of NFAT and the interaction between NFAT1 and the non coding RNA NFAT repressor (NRON) complex [ 42] in response to inducer of the innate immunity [ 43].
Noticeably, it has been found that the chain length of PDMAEMA brushes could influence the retention behavior of steroids due to the controllability of ATRP, which proposed an interesting alternative to modulate retention in HPLC.
Interestingly, this pathway can be modulated by nuclear retention of cPML via a mechanism involving TG-interacting factor (TGIF-) and c-Jun.
Various factors in the tumor microenvironment can modulate the recruitment and retention of BM-derived cells during the development of the tumor vasculature [37].
The mechanisms that could underlie such a control needs to be better resolved, but two-hybrid interaction experiments with AtNUP58 [ 13] and the absence of evidence for a direct interaction of AtNUP62 with SKP1 (Additional file 2: Figure S2) suggest that AtNUP62 might modulate the activity or nuclear retention of SKP1 in part via its interaction with AtNUP58.
Alternatively, duplex formation between sense and antisense RNA molecules can result in nuclear retention of antisense transcripts and modulate gene expression.
According to the results from the in vitro permeation and retention of KA, the formulations developed can modulate the permeation of KA in the skin.
In addition to increasing nuclear retention of XPO1 cargoes, SINE compounds also modulate the expression levels of several key regulatory proteins [ 9, 10, 37, 42].
