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Objectives Determine if exposure to septic serum modulates mitochondrial function in a live naïve kidney slice.
However, during the last decade, the transcription-independent activity of the p53 protein has emerged as an important mechanism by which p53 modulates mitochondrial function.
Exactly how LB2 modulates mitochondrial function still remains to be elucidated.
This discussion highlights the fact that much more work is required to understand how fusion modulates mitochondrial function.
Taken together, these results suggest that Clu directly modulates mitochondrial function, and that Clu's function contributes to the PINK1-Park pathway of mitochondrial quality control.
Additional interest on how nutrient scarcity modulates mitochondrial function comes from the fact that CR is the most consistent physiological intervention to improve health and extend lifespan across a wide range of organisms (Fontana et al, 2010; Houtkooper et al, 2010b).
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H2O2 has a major role in modulating mitochondrial function by inhibiting activities of the mitochondrial enzyme in a fully reversible fashion [3, 4].
In their turn, superoxide flashes modulate mitochondrial function, as they cause mitochondrial depolarizations.
Multiple kinases and phosphatases in mammals are identified to translocate to mitochondria and play critical roles in modulating mitochondrial function [64].
Growth factor-mediated pathways have been reported to modulate mitochondrial function and regulate the activity of the pro-apoptotic protein, BAD [15].
EGFR and Src can translocate to mitochondria by binding the subunit
More suggestions(16)
modulates mitochondrial competence
modulates mitochondrial transmembrane
modulates mitochondrial shape
modulates mitochondrial fragmentation
modulates neuroendrocrine function
modulates mitochondrial biogenesis
modulates mitochondrial activity
modulates mitochondrial membrane
modulates Oep function
modulates dopaminergic function
modulates neuronal function
modulates neutrophil function
modulates mitochondrial quantity
modulates osteoblastic function
modulates mitochondrial respiration
modulates mitochondrial metabolism
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