Sentence examples for modulates integrin expression from inspiring English sources

It will also be of interest to determine the precise mechanism whereby PTHrP modulates integrin expression.

Finally, we evaluated whether TGF- β2 modulates integrin expression of GL-261 and SMA-560 NS cells.

Based on the knowledge that MMF modulates integrin expression, we postulated that MMF might not only suppress leukocyte recruitment to the donor graft, but also prevent integrin-dependent tumor dissemination.

Taken together, we suggest that BM-PC may interact with extracellular matrix exposed at sites of angiogenesis or vessel repair, and that the Notch pathway is involved in this interaction by modulating integrin expression.

This would depend on the ability of the tissue microenvironment to modulate integrin expression and apoptosis resistance epigenetically in MECs.

We and others [ 19, 26, 27] have also observed that the ECM microenvironment can dynamically modulate integrin expression in both primary and immortalized MECs.

Overall, our results indicate a potential mechanism in which TβRIII modulates integrin-α2 expression to effect MSL cell migration, invasion, and tumorigenicity.

The intracerebral implantation of WJ-MSCs in experimental brain stroke increased brain plasticity and modulated β1-integrin expression, while also providing exogenous SDF-1α, BDNF and GDNF, which were found in brain areas adjacent to the infarcted tissue [ 48].

Integrin expression is modulated by several cytokines, growth factors and the extracellular matrix in different cell types [ 2].

Modulating cell-substratum adhesiveness by changing integrin expression level or activation state alters the ligand density required for maximum migration speed [43].

Integrin expression and activity can be further modulated by other transmembrane proteins such as tetraspanins or cell surface heparan sulfate proteoglycans.