MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability.
Huang S, Wu S, Ding J, et al. MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions.
Researchers used synthetic operons to systematically examine whether the number, length, or order of the genes in an operon modulates gene expression.
Jiang W, Bhagat L, Yu D, Kandimalla ER, Agrawal S. IMO-3100, an antagonist of Toll-like receptors 7 and 9, modulates gene expression and regulatory networks induced by ligands.
Indeed, Jaak Panksepp's neuroscientific research on mammals identified play as a primary human drive and the brain's source of joy, which is linked to the release of a specific neurochemical that modulates gene expression critical to the development of a child's social brain.
It is also known from cell culture studies that SUMOylation modulates gene expression.
Beta-catenin is thought to mediate cell fate specification events by localizing to the nucleus where it modulates gene expression.
MicroRNAs (miRNA) are small endogenously transcribed regulatory RNA which modulates gene expression at a post transcriptional level.
Upon activation, this kinase cascade modulates gene expression through the phosphorylation and inhibition of transcription co-activators that are involved in cell proliferation, differentiation, growth and apoptosis.
Calcineurin, a calcium/calmodulin-regulated protein phosphatase, modulates gene expression in cardiac and skeletal muscles during development and in remodeling responses such as cardiac hypertrophy that are evoked by environmental stresses or disease.
In the sugar signaling pathway, HXK1 is a glucose sensor that modulates gene expression and multiple plant hormone-signaling pathways underlying sugar sensing and signaling in plants (Pego et al. 1999; Jang et al. 1997).
