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In particular, Fiaccavento et al. have demonstrated that supplementation of dystrophic UM-X7.1 hamsters, carrying a phenotype similar to limb girdle muscular dystrophy 2F (LGMD2F) with ALA, precludes myocyte and muscular tissue damage and modulates cells proliferation promoting myogenic differentiation.
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The results show that extracellular thiol/disulfide redox state modulates cell proliferation rate and that this control interacts with growth factor signaling apparently independently of cellular glutathione.
These recent data show for the first time that PiT1, in addition to its retrovirus receptor and Na+-Pi cotransporter functions, modulates cell proliferation in vitro.
Heparan sulphate proteoglycan syndecan-1 modulates cell proliferation, adhesion, migration and angiogenesis.
These results suggest that TGFBI modulates cell proliferation and neoplastic transformation phenotypes.
To investigate whether Nrf2 modulates cell proliferation in HCC cells, we assayed its effect on cell proliferation activity.
Connected circuits involve SOX9, an important cancer gene, a TF which antagonizes β-catenin, inhibits TCF activity in cancer cells and modulates cell proliferation [ 49].
We report herein that perturbation of JMJD6 expression modulates cell proliferation and cell scattering and motility: phenotypes associated with cancer metastasis.
The present results showed that TWEAK modulates cell proliferation and MCP-1 production in glomerular mesangial cells in a dose-dependent manner.
Transforming Growth Factor Beta (TGF-β) signaling modulates cell proliferation and induces production of growth factors, angiogenic factors, extracellular matrix proteins and proteases in fibroblasts.
Hyperactivity of Akt/PKB is a hallmark of most human forms of cancer, given that it modulates cell proliferation, growth, survival, and transit metabolism.
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