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This, coupled with the stacking defect in mild mutants, suggests that Hsp90 activity modulates a role for Gata3 in neural crest cell movements underlying palatogenesis.
Thus if ATR regulates the prevention by WRN of fork breakage, is it possible that ATM modulates a role of WRN during repair of DSBs formed at collapsed forks?
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This interaction between BRCA1 and DBC1 was physiologically functional because our results indicated that the DBC1-containing complex might modulate a role of BRCA1 in living cells, repressing BRCT function.
Simultaneous activation of Wnt and mTOR pathways suggests crosstalk, which is consistent with previous studies demonstrating that overactive Wnt signaling modulates mTOR and plays a role in tumorigenicity.
In this respect statins play a role modulating immunological activity [ 63- 65].
The work of Somel et al. (19) extends to mammals the possibility of a developmental clock modulating aging and suggests a role for miRNAs in this process.
Regulation of a biological process is defined as a role that modulates the frequency, rate or extent of that process.
Melatonin also plays a role in modulating certain functions of the immune system.
However, neurotransmitter systems may have a role in modulating spreading activation.
This phenomenon suggests that ovarian hormones might play a role in modulating CNCP pain.
Glucagon-like peptide-1 (GLP-1) plays a role in modulating neuroendocrine and autonomic function.
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