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The findings suggest that future cage designs may be modulated to target desired mechanical strain regimes at physiological loads.
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Furthermore, the ability to reduce the volume of normal lung receiving low doses was limited, because the intensity of the static beams could not be modulated to achieve good target conformity.
Thus, the beam may be tuned by modulating its energy to target the tumour without damaging the tissues located at a deeper position [see Fig. 1)].
Furthermore, temperature-dependent phosphorylation of CCA1 modulates its binding to target gene promoters [ 24].
The sex steroid hormone-binding globulin (SHBG) gene regulates the action of sex steroid hormones by modulating their bioavailability to target tissues such as the ovaries [ 4].
Jarid2 has DNA binding activity and modulates PRC2 recruitment to target genes (Li et al. 2010).
Moreover, nanobodies, single variable domains of heavy chain camelid antibodies, are being investigated for their potential to target and modulate the function of receptors like CXCR4.
One of the effective ways to modulate HIV-1 infection is to target viral proteins; among the viral proteins, Tat plays a major role in HIV-1 pathogenesis.
miRNAs are ~22-nucleotide small noncoding RNAs that modulate gene expression by binding to target mRNA by imperfect complementary, causing either mRNA degradation or translation inhibition [ 5].
The C2, PX and PH domains have been implicated in protein-protein interactions, but perhaps their best described function involves their ability to modulate membrane targeting of proteins.
Our group used the proteomic approach to search for new chemotherapeutic leishmanial targets and to modulate these targets to control Leishmania infection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com