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We assumed that there probably exists a delayed effect when genes are modulated to function in a certain process.
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Untangling the events would be an essential first step to developing a method to modulate BCRP function to aid patients with cancer.
Pharmacologic approaches to modulate mitochondrial function have, to date, been limited and have recently been reviewed [ 2, 3].
We postulated that TFEB uses the v-ATPase/mTORC1 sensing device on the lysosomal surface to modulate lysosomal function according to cellular needs.
Two protein kinases, Yak1 and Rim15, have been reported to modulate Msn2 function in response to PKA activation (see [ 5] for a review).
Our results thus suggest that epigenetic modifications constitute a primary response to elevated sleep pressure showing the potential to integrate different brain processes, and to modulate synaptic function notably by affecting the expression of synaptic elements.
Two synthetic retinoids known to modulate the function of mammalian RXR were used to target worm viability in vitro.
During recent years, studies have been undertaken in an attempt to modulate DC functions or to reprogramme Th differentiation [ 111– 111].
Signaling focal contacts via ITGβ3 were identified to facilitate cell adhesion, migration and mediate ECM-physical cues to modulate HSPC function.
Several synthetic modulators of the CaSR have been developed in order to modulate CaSR function.
If the issue is autoimmune in nature (which it usually is), we also work to modulate the immune function in order to avoid further inflammatory damage to the thyroid gland," says Warner.
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CEO of Professional Science Editing for Scientists @ prosciediting.com