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Accumulating data suggest that the vasculo-protective functions of EPCs may be used as cellular biomarkers for endothelial damage, or may be pharmacologically modulated to enhance the body's defence to atherosclerosis.
First, the input features are modulated to enhance the contrast of a searched object with respect to other regions in the scene.
The recognition of this exclusive role for the osteoclast in all pathologies involving bone loss (osteoporosis, arthritis, periodontal disease) has identified a single cell whose function can be modulated to enhance or reduce bone loss [ 1].
These findings provide fundamental insights into the functional plasticity of the human B cell compartment, and also suggest that B cells could be modulated to enhance vaccine efficacy, particularly in malaria endemic areas.
While costal chondrocytes demonstrate phenotypic alterations in monolayers similar to articular chondrocytes, including decreased type II collagen and glycosaminoglycan expression [ 8, 10], previous work has shown that expansion and three-dimensional redifferentiation culture conditions may be modulated to enhance hyaline cartilaginous matrix production post expansion [ 3, 8, 9].
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It could be possible to alter PHR1 or SPX1/SPX2 in such a way that the low-Pi response could be modulated to activate processes that enhance Pi uptake and assimilation while preventing the drastic reduction in shoot growth that is generally observed in Pi-starved plants.
Restoration of miR-129 levels could be a future direction to develop a novel therapeutic strategy to modulate and to enhance chemosensitivity to 5-FU treatment.
Here we discuss the current methods to 1) derive functional SMC from iPSC, 2) model vascular diseases using SMC generated from patient-derived iPSC, and 3) modulate microenvironmental cues to enhance cellular differentiation and functionality and better mimic the physiological environment.
Bacteria are able to modulate their metabolism to enhance survival during periods of environmental change.
Thus, our findings will help define a new strategy in modulating radiation therapy to enhance clinical efficacy in the treatment of patients with NSCLC.
This study also suggests that CSFV can modulate host-signalling pathways to enhance its persistence and survival.The exact mechanism of the modulation remains to be elucidated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com