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Moreover, we showed that CUDC-101 modulated the function of both transporters without affecting the protein expression of either ABCB1 or ABCG2.
In order to determine the cellular mechanisms that regulate resting membrane potential (RMP) in the native clock of Drosophila we modulated the function of Shaw, a widely expressed neuronal potassium (K+) channel known to regulate RMP in Drosophila central neurons.
To investigate if the observed interaction also modulated the function of T lymphocytes, purified CD3+ cells were co-cultured with viable H. pylori, using fixed bacteria as a control, to assess the up-regulation of CD69, known to be an early activation marker antigen of lymphocytes.
We modulated the function of XIAP, either through its constitutional downregulation with an shRNA vector or by applying a Smac-mimicking peptide.
We also attempted to explore whether the CXCR2 agonist IL-8 also modulated the function or potency of DOP receptor agonists.
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The PAG modulates the function of the nucleus ambiguus [14].
Membrane cholesterol plays an important role in modulating the function of several membrane proteins.
Small molecules have been used successfully to modulate the function of the bacterial ribosome, viral RNAs and riboswitches.
Describing, understanding, and modulating the function of the cell require elucidation of the structures of macromolecular assemblies.
Additional domains coupled to the same polypeptide are important for modulating the function of these ubiquitin ligases.
Recently, aptamers have proven to be valuable tools for modulating the function of endogenous cellular proteins in their natural environment.
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modulated the activation
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modulated the diversity-invasibility
modulated the vasodilation
modulated the capacity
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modulated the responsiveness
modulated the amount
modulated the microbiota
modulated the significance
modulated the transcription
modulated the band
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