Sentence examples for modulated positively from inspiring English sources
In mouse retina, glial cell fate specification is modulated positively by the bHLH gene Hes5 [6], [6].
However, HMGB1 extracellular activities can be modulated positively or negatively, by oxidation in necrotic and apoptotic cells [3] [5] [4] and/or by interactions with a large set of molecules of cellular or viral origin [8].
Consistent with redistribution of tBid being functionally important, it was modulated positively and negatively by pro- and anti-apoptotic Bax and Bcl-XL, respectively.
As expected from PCA, the two most populated clusters were number 4 and 8, composed by genes modulated positively and negatively from TP B to TP C, respectively.
Components of these pathways are modulated positively or negatively in the presence of PAX3-FKHR suggesting that Pax3 fine-tunes Wnt and Shh signalling, probably also limiting the spatial extent of their action in the somite (see Additional file 1 Figure S1 for Zic1).
Specifically, miR-146a, miR-155, and let-7i are microRNAs that are modulated positively when DCs are exposed to maturation agents including LPS, TNF, and IFN- γ [ 18, 19] and seem to be related to the activation events triggered in DCs by such stimuli including the expression of costimulatory molecules, secretion of proinflammatory cytokines, and even induction of apoptosis [ 16– 16].
In our attempt to model OGD-induced neuroblast activation, we took into account other factors which can modulate, positively or negatively, migration from the SVZ to the cortex.
Thus, we propose that Tbx1, by modulating positively the FGF and negatively the BMP-Smad1 signaling systems plays a central role in the homeostasis of cardiac progenitor cells of the SHF.
NK cells are also able to modulate positively or negatively the adaptive immune response via secreted products.
Moreover, HIPK2 was reportedly able to modulate positively the protein content and transcriptional activity of PDX1, and directly phosphorylate the C-terminal portion of PDX1 [17].
In addition, this is supported by the fact that SDG724, a rice histone methyltransferase gene, that is required for flowering under LD conditions modulates positively EHd1 and RFT1 expression, but not Hd3a[ 24].
