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The 70 80 Hz signal that we have recorded during olfactory stimulation can be modulated in opposite directions by two different protocols.
However, brain activation was modulated in opposite ways by depletion in each group.
We observed that the levels of sense and antisense intronic RNAs at the DNAJC3 locus were modulated in opposite directions after androgen treatment.
Taken together, these findings indicate that polyA stretches can form α-helical CC structures that are even more stable that those formed by polyQ stretches and that the CC folding of polyA stretches can be modulated in opposite directions by appropriate CC-stabilizing or -destabilizing substitutions.
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These initial data suggest that bisphosphonates and FGF-2 can modulate in opposite directions the phosphorylation status of common signalling pathways such as MAPK, which is involved in the balance between induction of and protection against cell death.
Gene expression can be modulated in two opposite directions, towards higher or lower amounts of product.
We next wondered whether the 70 80 Hz response could be modulated in the opposite direction.
Hence, even if the Nc is affected by these stimulus-locked ERPs it should have been modulated in the opposite direction, i.e. there should be a reduction of the Nc in de novo-PDs, which was not the case.
Two miRs were modulated in an opposite manner in IFN-β-treated Huh-7 cells and in 21-5 replicellsells.
Five genes appeared to be modulated in the opposite direction by qRT-PCR (AXL, IFNA4, DLG1, TNFRSF9 and SIN3A).
Moreover, pharmacological and genetic manipulation of the mTOR pathway modulated in an opposite fashion signaling to S6K/S6 and cell viability in nutrient-repleted medium.
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