Sentence examples for modulated genes are from inspiring English sources

In the TDI primary chondrocyte cultures, several differently modulated genes are involved in adhesion and cytoskeleton dynamics and regulate or act along the Rac1 and CDC42 RhoGTPase signaling pathways.

While a large proportion of miR-181b associated changes can be attributed to the presence of corresponding MREs or E2F1 binding motifs (52% in HEK-293 and HeLa cells; 70% in SH-SY5Y cells), this proportion increases significantly to over 80% in HEK-293 and HeLa cells when only bidirectionally modulated genes are considered (Additional file 4: Figure S3).

Moreover, some modulated genes are related to scaffold proteins, e.g. CNKSR2, IQGAP3, LSP1 (down-regulated) and NME1 (up-regulated).

In addition, about eight percent of the modulated genes are related to extracellular matrix (ECM) structure and dynamics (Figure 5).

A high number of modulated genes are involved in glycosaminoglycan (GAG) and proteoglycan biosynthesis, diversification and sulfation.

From the numbers of up- versus downregulated (170 versus 462) transcripts it is easily seen that the bacteria upregulates a selection of stress response genes, while the majority of modulated genes are downregulated to focus on the repair process.

These results demonstrated that the spike-based normalization is interchangeable with global normalization algorithms under condition in which the representation of modulated and not modulated genes is symmetric such as that shown in Figure 8A.

In the TGR-1 cells, 430 of 989 rapamycin modulated genes were in the set of c-Myc targets, far exceeding the expected 192 genes (P<0.000001).

In addition to these changes, an assortment of transcriptionally modulated genes was observed, which would function to maintain the level of constituents for the PG-pentapeptide precursor.

When these significantly modulated genes were analyzed, according to the biological process, we could not identify any enriched GO terms for those genes whose expressions were down-regulated over time.

Tentatively, 240 and 60 modulated genes were identified as unique to EE or TAM, respectively.