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In the same time, some AS events possibly modulated functions of proteins with multiple domains.
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In this paper a consistent approach for the design of FIR differentiators by means of modulating functions is proposed.
He is co-developer of nanoparticulate formulations of thyroid hormone analogues, such as tetraiodothyroacetic acid, that act exclusively at the hormone receptor on the integrin to modulate functions of the integrin.
The PI3K/Akt pathway can modulate functions of ABC transporters through various mechanisms.
These examples showed that some AS events can modulate functions of proteins especially for ones with multiple domains.
Calmodulin expresses modulating function by conformation change with calcium binding.
Such assemblies provide additional mechanisms by which to modulate function.
Glucocorticoid regulation has been shown to modulate function in NOTCH, VEGF, TGFB and WNT signalling [ 30].
For membrane proteins, lipids provide a structural framework and means to modulate function.
In addition to differences in peptide sequence and concentration, aggregation state also modulates function.
Importantly many nontoxic, naturally occurring small molecules are now known to modulate function of or increase expression of HSPs.
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