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Inhibition of endogenous versican expression by siRNA or reduction of versican G3's expression by linking G3 with 3′UTR prevented G3 modulated cell apoptosis.
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When combining concentration of 200 nM doxorubicin and 100 μM hesperidin together in treating with MCF-7 cells, they increased cytotoxic effect, modulated cell cycle, and induced apoptosis of MCF-7 cells [ 42].
CDHA modulated cell cycle regulatory proteins and apoptosis-related proteins in a manner similar to that of parent DHA.
The methanol extract perturbed cell cycle progression, modulated cell cycle and regulated, signal molecules were involved in induction of apoptosis in HepG2 cells.
Moreover, cell apoptosis was assessed using Annexin V-FITC/PI apoptosis Kit (Thermo Fisher Scientific, USA).
(A) Representative flow cytometry plots of cell apoptosis.
NgR1 expression and cell apoptosis in different groups.
Cells under hypoxia showed cell cycle arrest and lower cell apoptosis.
Furthermore, HMGB1 siRNA inhibited cell viability and promoted cell apoptosis in SW982 cells following OMT treatment.
Pirh2 shRNA prevented bortezomib-induced cell apoptosis.
(A) BMP7 induces breast cancer cell apoptosis.
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