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Exact(5)
These observations suggest that HCN channel function is likely to be modulated by regulatory proteins and β-subunits in myocardial tissue.
Further downstream, we found that biochemical constraints on indole glucosinolates are modulated by regulatory changes.
The activity of Atmir399 is itself modulated by regulatory RNAs AtIPS1 and AtAT4, which are thought to mimic the AtPHO2 transcript and compete for Atmir399 binding [ 23].
Again, as seen in patients with RA, the activity of CD4+CD28null T cells can be modulated by regulatory receptors of the KIR family [ 84].
Akt, a serine/threonine protein kinase, is phosphorylated through the PI3K pathway and is important in regulating cell cycle progression [ 11], which is modulated by regulatory factors, including cyclin and CDKs, with pRb considered an important inhibitor of proliferation [ 5, 10].
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Physical interactions between cis-regulatory elements and gene promoters can be identified by chromatin conformation capture methods, which provide mechanistic evidence to support hypotheses regarding the role of distal regulatory elements in modulating expression of particular genes and how this may be modulated by specific regulatory genetic variants.
HCN channel subunits (HCN1-4) are believed to be modulated by additional regulatory proteins, which still have to be identified.
Dopa decarboxylase activity can be modulated by different regulatory factors.
Phosphorylation/dephosphorylation of cofilin at Ser 3 is modulated by multiple regulatory kinases and phosphatases.
Like most other genes it is likely that the APP promoter is modulated by distal regulatory sequences.
Hepatic GCK activity is modulated by glucokinase regulatory protein (GKRP; gene symbol GCKR), a competitive inhibitor of GCK.
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modulated by regulation
modulated by regional
modulated by noradrenergic
modulated by Ta
modulated by extracellular
modulated by cytokine
modulated by free
modulated by motivational
modulated by retinoic
modulated by glucocorticoid
modulated by external
modulated by multi-site
modulated by post-translational
modulated by several
modulated by exogenous
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