Neuronal action potentials are generated and modulated by a precise combination of ionic currents produced by the activity of ion channels.
Very often, the pattern of AS was tissue and developmental stage specific, thought to be under precise regulation modulated by cooperative interplays between trans-acting RNA binding proteins (RBPs) and cis-regulatory elements in nascent transcripts (Barash et al, 2010; Black, 2003; Chen & Manley, 2009; Witten & Ule, 2011).
Activation and inter-regional synchronization in this network is modulated by theta phase but, paradoxically, the precise relationship to theta oscillations differs between sources and source pairs.
Bearing in mind the broad range of signaling activities of TIMP-1 in other cell types, it would be important to dissect the precise signaling pathways modulated by TIMP-1 that affect neuron viability before implementation of TIMP-1-delivery therapy for CNS neurodegeneration.
The data are modulated by 16QAM modulation.
However, the exact phosphosites modulated by UBLCP1 were not identified.
The precise nature and content of 'generic' self-evaluation is presumably modulated by other brain systems, as evidenced by patterns of increased and decreased activation on fMRI in posterior cerebral regions (PCC, precuneus, occipital cortex) and other more lateral frontal, parietal and temporal regions.
These data suggest that FRs may be modulated by gap junctions, although additional experiments in vivo will be necessary to determine the precise role of gap junctions in this pathological activity associated with epileptogenesis.
The precise mechanisms by which Wnt5a leads to NFAT activation and in turn how Wnt5a activity is modulated by NFAT remain to be determined.
Precise distinction of ripening stages led to stage-specific detection of malic acid and anthocyanin-related transcripts modulated by heat stress.
