Sentence examples for modulated by phosphorylation from inspiring English sources

In this study, we show that the activity of PstP is modulated by phosphorylation.

There is also evidence that the function of Twist can be modulated by phosphorylation [11], [12].

Such interactions are frequently modulated by phosphorylation, which requires disorder in the target protein both for optimal kinase accessibility and for subsequent accessibility of the binding motif [44], [45].

While we cannot exclude the possibility that Foxc function is, in part, independent of VEGF signaling, activity of Foxc proteins may be modulated by phosphorylation in response to VEGF.

More recently, it has become clear that ERβ function can also be modulated by phosphorylation in its N-terminal region, so coupling ERβ activity to growth factor signaling [20].

This idea is supported by evidence that human FOXC1 and FOXC2 are phosphorylated by EGF stimulation [40], [41] and that human FOXC1 activity is elaborately modulated by phosphorylation levels [40], [42].

These results suggested that in addition to protein interaction events, the function of M2 could be modulated by phosphorylation-based signals.

1, 2 Both ligand-dependent and ligand-independent activation of the ERα is modulated by receptor phosphorylation, and receptor phosphorylation is enhanced by ligand binding.

As the signalling potential of the docking protein is highly modulated by its phosphorylation status, we set out to obtain more insights into the impact of TKIs on Gab2 phosphorylation.

Altogether, our data support a role for L-plastin in the control of actin turn-over which is modulated by its phosphorylation on residue Ser5.

Applying in-cell biochemistry using NMR spectroscopy to the ternary Ubiquitin-Hrs-STAM2 complex showed that the interaction surface is significantly modulated by the phosphorylation state of two STAM2 tyrosines, Y371 and Y374, located in the conserved ITAM domain.