Sentence examples for modulated by nAChRs from inspiring English sources

Besides pyramidal neurons, also interneurons are modulated by nAChRs.

We hypothesized that interneurons in cortical layers II/III and VI are also modulated by nAChRs.

It is also unknown whether layer VI interneurons are modulated by nAChRs.

Whether layer II/III pyramidal neurons in the PFC are modulated by nAChRs is not known.

In contrast to layer V, excitatory glutamatergic inputs to layer VI pyramidal neurons were mildly modulated by nAChRs.

These findings show that only a minority of layer II/III pyramidal neurons are modulated by nAChRs.

As was reported (Kassam et al. 2008), we found that these neurons are modulated by β2* nAChRs that are responsible for the strong activation of the layer VI neuronal population.

Layer VI pyramidal neurons in entorhinal cortex also have been reported to be modulated by non-α7 nAChRs, most likely containing β2 subunits (Tu et al. 2009).

These data show that excitatory inputs to layer VI pyramidal neurons are mildly modulated by ACh through nAChR activation.

Here, we investigate nAChR modulation of all PFC layers and find marked layer specificity for pyramidal neurons: LII/III pyramidal neurons and glutamatergic inputs to these cells do not contain nAChRs, LV and LVI pyramidal neurons are modulated by α7 and β2* nAChRs, respectively.

Pyramidal neurons in layer VI of the PFC are modulated by α5-containing β2* nAChRs (Kassam et al. 2008).