HOX co-factor UNC-62 (Homothorax) has been identified as a developmental regulator that binds proximal to age-regulated genes and modulates lifespan by integrating RNAi and genomics approach [ 39]. C. elegans FOS-1 has been shown to act in uterine and vulval development, which regulates plc-1 expression in the spermatheca to control ovulation [ 4].
Thus, cells would modulate gene expression by integrating AJ status with Wnt-like external signaling.
The influence of the wnt signalling on the target cells is modulated by a complex regulatory network integrating various inputs including the level of ligand-receptor interactions and the diversity of downstream transcriptional complexes.
In short, hemodynamic status is modulated by the nervous system during exercise by integrating signals originating from the brain (central command) and from the periphery (exercise pressor reflex, baroreflexes, and arterial chemoreflex).
Although individual Msn2 target genes can only transduce little information, we illustrate how the cell can improve information transduction capacity by modulating promoter cis-elements, by integrating the response of more than one gene, or by having multiple copies of the same gene.
It is a highly integrated process modulated by multiple signaling pathways, consisting of cytoskeleton extension and focal complex formation at the front, and focal adhesion disassembly and cytoskeleton contraction at the back [1].
The HSNs are modulated by the VC neurons, and also integrate environmentally-controlled neuromodulatory signals that influence egg-laying frequency.
We suggest that the neurons were more strongly modulated by the sensory cues and thus integrated all the information pertaining to the sensory cues.
The data are modulated by 16QAM modulation.
In both groups and within the two categories, the ACE was found and therefore, language-induced motor effects were likely modulated by the whole sentence (when information was integrated).
