Sentence examples for modulated by estrogen from inspiring English sources

Moreover, substantial evidence from in vitro studies suggests that cytosolic and mitochondrial CK expression is modulated by estrogen receptor-mediated gene activation [8 10].

The model explains why MCF7 sub-clones transfected with HER2 or EGFR show three GFR-distribution patterns, and why the bimodal distribution pattern can be reversibly modulated by estrogen.

This social hormone appears to be particularly important in determining the behavior of females as its effects are strongly modulated by estrogen [34], and oxytocin responses to stress are more commonly observed in females [e.g., 35].

In the brain, the actions of IGF-1 are modulated by estrogen receptor alpha (ESR1), which directly interacts with several components of the IGF-1 transduction pathway including IGF-1R and IRS1 [51].

Fifteen genes were selected and all were modulated by estrogen in vitro.

Heparanase gene regulation is also modulated by estrogen, which is an important risk factor for breast cancer.

Because concurrence of both oocyte maturation and cervical mucus liquefaction is modulated by estrogens before the midcycle, any perturbations to the endogenous estrogenic milieu caused by endocrine disruptors may theoretically affect sex ratio (Jongbloet 2004).

WNT/β-catenin signaling is modulated by estrogens in breast cancer [ 32] and neuronal cells [ 33], and endogenous estrogens have been found to protect against APC-associated tumor formation in mice, associated with an increase in ERβ and a decrease in ERα expression in the target tissue [ 34].

Because angiotensinogen production by the liver is modulated by estrogens, the assumed increase in the serum isoflavone concentrations due to the high isoflavone intake may have stimulated an estrogenic response, thereby increasing hepatic angiotensinogen production and release into the plasma [ 9- 11].

The data suggest that GSNO-R activity is modulated by both estrogens and androgens in conjunction with hormonal regulation of eNOS to maintain S-nitrosothiol homeostasis.

Thus this study defines estrogen responsive genes as genes that can be modulated by an external estrogen source.