At the skin level, the sebaceous gland activity is obviously modulated by these endocrine fluctuations.
It is modulated by the endocrine and nervous systems and there is growing realization of its multifunctionality.
In retrospect, given the number of cellular pathways affected by the mevalonate pathway, TGF-β family members, and hormones affected by menopause, it is not surprising that the likely anticancer effects of ZOL, in and outside of bone, may be modulated by the patient's endocrine environment.
Epidemiological, clinical, and experimental data indicate that the risk of developing breast cancer is strongly dependent on the ovary and on endocrine conditions modulated by ovarian function, such as early menarche, late menopause, and parity.
Although the reasons for this increase are not certain, epidemiological, clinical, and experimental data indicate that the risk of developing breast cancer is strongly dependent on the ovary and on endocrine conditions modulated by ovarian function, such as early menarche, late menopause, and parity [ 1- 3].
Furthermore, as shown for body weight regulation and obesity but might also apply to other endocrine axes, the set points for endocrine axes are modulated by the maternal "environment" of the fetus (Plagemann 2005); this process could be disturbed by the influence of EDCs.
The data are modulated by 16QAM modulation.
Thus, the response to endocrine therapy does not appear to be strongly modulated by whether the source of estrogen is autocrine or endocrine.
Here, we investigated whether endocrine cell development is modulated by ROS in the embryonic pancreas in vivo.
