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This suggests that their respective activities are modulated by distinct genetic loci.
RANKL, RANK and OPG are all expressed in the inflamed synovium of RA and specifically modulated by distinct anti-rheumatic drugs.
Thus, these studies delineate a critical role for mTORC1 signaling in RBC growth, development, and proliferation, and define how this pathway is selectively modulated by distinct pharmacologic, genetic, or nutritional perturbations leading to anemia.
Our results also indicate that Puf3p activity is modulated by distinct loci, depending on whether it acts via the 5′ or the 3′ untranslated region of its target mRNAs.
In particular, β2*nAChRs have an ubiquitous role in modulating neurotransmitter release in the PFC and thereby the behaviors and cognitive processes modulated by distinct neurotransmitter systems in this region, including attentional processing (19), working memory (20, 21), reward-related processing and learning (22), as well as flexible decision-making (23, 24).
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T3SS expression is also modulated by several distinct environmental signals [3], [15], ensuring that the system is available by the time the bacterial pathogen reaches the distal small intestine, where invasion of the epithelial monolayer takes place [5].
mTORC2 and SGK-1 therefore determine how mechanisms that increase lifespan are modulated by two distinct environmental inputs, bacterially produced signals and temperature.
This post-synthetic modification introduces PARs [poly(ADP-ribose) polymers] on to chromatin proteins and is peculiar since target proteins can be modulated by two distinct mechanisms: covalent and non-covalent PARylation [ 3– 5].
Fundamental cell biological processes such as autophagy are modulated by many distinct inputs such as host metabolism, amino acid availability, oxygen levels, and innate immune pathways (Choi et al, 2013).
Areas modulated by emotion were distinct from those modulated by memory load.
This observation suggests to us that the activation mode of RelA is modulated by association of distinct coactivators, discussed below.
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modulated by different
modulated by noradrenergic
modulated by regional
modulated by Ta
modulated by extracellular
modulated by cytokine
modulated by free
modulated by motivational
modulated by retinoic
modulated by external
modulated by glucocorticoid
modulated by multi-site
modulated by post-translational
modulated by exogenous
modulated by several
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