Sentence examples for modulated by compounds from inspiring English sources

39 Homologues of these targets are present in T. brucei and could therefore be modulated by compounds of this series.

VGSCs, like other voltage-gated ion channels, can be differentially modulated by compounds that bind selectively to distinct conformational states of the channels.

We believe that the reason for this variation is that an essential molecular target or targets is present in the T. brucei parasite which can be modulated by compounds with a similar pharmacophore to that required for TbGSK3 inhibition.

While pain control and epilepsy are still the major focus of interest in terms of sodium channel drug development, it remains possible that indications ranging from autism to immune disorders may be modulated by compounds targeted at sodium channel activity.

Similarly, most of the genes altered in the normal HBEC30KT cells were not modulated by compound 5 in the cancer HCC4017 patient-matched line.

Intrinsic self-assembly, and higher-order assembly tightly modulated by aromatic compounds, provide insights into the formation of multilayer reflectors in iridophores and spherical microparticles in leucophores and may form the basis of structural color change in cephalopods.

Courtship between flies is modulated by these compounds.

Despite the different topologies and gene compositions of the networks, a number of common pathways that were modulated by all compounds and were also present in all sub networks.

In fact, various cell death pathways are modulated by these compounds, depending on the cellular context.

We have recently reported that implantation of a synthetic matrix in the peritoneal cavity in mice induced a fibroproliferative process whose components, inflammatory cell recruitment, angiogenesis, and extracellular matrix deposition were identified and modulated by various compounds [ 9, 10].

Whereas the screening endpoint - nuclear p27 - was robustly modulated by the compounds, SMIP-mediated cell cycle arrest and apoptosis were not strictly dependent on p27 and p21 - a finding that is explained by parallel inhibitory effects of SMIPs on positive cell cycle regulators, including cyclins E and A, and CDK4.