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These effects may be modulated by SNPs in selected genes.
The MREs predicted to be modulated by SNPs have a good miRSVR score and total context score indicating their functional significance.
Similar(58)
We propose that the effect of these changes, reflected by the high prevalence of subjects with obesity, high FPG, and serum lipids disorder, was modulated by UCP2 SNPs.
Based on the cis QTL analysis mRNA expression of VPS52, TAPBP, and B3GALT4 as well as methylation of VPS52 were modulated by these SNPs.
Future studies are needed to clarify the underlying mechanisms by which cancer or smoking-related phenotypes are modulated by this SNP.
We assessed in 1,408 postmenopausal breast cancer patients from the German MARIE study whether cancer specific survival after adjuvant chemotherapy, anthracycline chemotherapy, and radiotherapy is modulated by 127 Single Nucleotide Polymorphisms (SNPs) in 21 BER genes.
Sebastiani and Perls [ 19] provide the rationalization for the approach of Schlosberg et al. [ 53]: being a complex trait, one would expect the presence of disease to be modulated by a large number of SNPs.
The data are modulated by 16QAM modulation.
The differential results of the association study as reported previously could be due to the outcome of various single-nucleotide polymorphism (SNP)–SNP and SNP environment interactions, again modulated by population and disease type.
In OA, evidence of interplay between genetics and epigenetics has been reported for the functional SNP rs143383, with its effect on GDF5 expression being modulated by DNA methylation (34, 35), and for the DIO2 SNP rs225014 (36).
All of the above observations indicate that DAF is modulated by the functional and structural consequences of exonic SNPs.
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