Sentence examples for modulated DEGs were from inspiring English sources
It is noteworthy that in all of the other contrasts, no oppositely modulated DEGs were observed.
Furthermore, significantly modulated DEGs were determined by a paired Student's T-test using p value < 0.05 [ 1].
The significantly modulated DEGs were compared with 62 genes affected by TCDD in both rat and mouse hepatic tissue from the studies of Boverhof et al. [ 8] (32 genes) and Boutros et al. [ 41] (33 genes).
For instance, focusing on T vs N up-regulated DEMs, miR-182 is involved together with miR-21, miR-18a, miR-1246 and miR-183 in the modulation of cancer-related pathways, and with miR-150 and miR-183 in the reprogramming of energy metabolism (purine and selenoaminoacid metabolism), in which various down-modulated DEGs were found, including ENTPD5.
In the TFs GO term (GO 0003700) a total of 253 DEGs were identified, thus representing the richest class of modulated genes in our experiment, with ARB vs. VOL showing the highest number of loci (165) and CAR vs. GV the lowest (34) (Table 2 and Additional file 5).
However, more down-regulated DEGs were restrained.
Around 385 DEGs were retrieved from Dictybase12.
DEGs were used as an input (up and down-regulated DEGs were analyzed separately).
More specific upregulated DEGs were identified in ZC108 (2235 DEGs) than in LJ43 (844 DEGs) at 72 hpi, while the number of specific downregulated DEGs decreased in the ZC108 (800) dramatically, reversely increased in the LJ43 (1793; Fig. 3b).
A total of 2,058 DEGs were characterized in Y vs G, with the most up-regulated DEGs (1,070).
