Sentence examples for modulate vascular remodeling from inspiring English sources
These data provide important targets for future studies to modulate vascular remodeling.
Furthermore, NO can modulate vascular remodeling independently of BP, which contributes to the maintenance of high BP [ 21, 79].
In addition, recent data showed that pharmaco-therapeutic interventions using pioglitazone can modulate vascular remodeling biomarkers such as VEGF concentration in ischemic tissue independent of peroxisome proliferator-activated receptor gamma stimulation [ 37].
Our results are in agreement with previous studies indicating that antioxidant therapies modulate vascular remodelling after injury [ 17, 22, 30, 31], although different mechanisms have been proposed depending on the animal model.
Adiponectin is a biologically relevant modulator of vascular remodeling linking obesity and vascular disease.
Carbon monoxide (CO) is an endogenous messenger that suppresses inflammation, modulates apoptosis and promotes vascular remodeling.
Our results indicate that Dicer is required for vascular development and regulates vascular remodeling by modulating VSMC proliferation and differentiation.
Additionally, miR-126 in ECs regulates vascular remodeling by modulating the expression of stromal cell-derived factor-1 (SDF-1) [ 20].
Intratumoral angiogenesis, endothelial cell proliferation, and matrix and vascular remodeling are modulated by HIF-1 via upregulation of VEGF, endothelin 1 (EDN1), plasminogen activator inhibitor 1 (PAI1, SERPINE1), (inducible) nitric oxide synthase 2 (NOS2), angiopoietin (ANGPT) 1 and 2, erythropoietin (EPO), and transforming growth factor (TGF -β3 (TGF -β3[ 299, 319] (Fig. 5).
Increased levels of vascular ROS may induce vascular endothelial dysfunction through the superoxide-mediated inactivation of endothelium-derived vasodilator nitric oxide (NO) as well as modulate intracellular signaling pathways that promote vascular remodeling [ 21].
Functionally, it is involved in inflammation-mediated vascular remodeling [46], is modulated during myogenesis, and plays a role both in the progression from myoblasts to myocytes and in the achievement of the fully differentiated phenotype [47].
