Sentence examples for modulate vascular inflammatory from inspiring English sources

By inhibiting mevalonate synthesis, statins can further modulate vascular inflammatory responses by reducing leucocyte migration via a mechanism involving the monocyte chemoattractant protein-1 (MCP-1) [52].

Thus PASMC ET-1 may modulate vascular tone independently of ET-1 produced by EC.

The endothelium has the capacity to modulate vascular structure in response to hemodynamic stimuli.

Moreover, monocytes/macrophages also modulate vascular calcification in vitro [ 27].

Endothelial cells are the gate keepers of vascular inflammatory signaling.

The same group [ 31] also showed that omentin inhibits TNF-α induced COX-2 expression by inhibiting the JNK signaling pathway in human umbilical vein endothelial cells, suggesting that omentin might prevent atherosclerosis by modulating the vascular endothelial inflammatory state.

While the circulating RAS is mainly responsible for blood pressure control and fluid and electrolyte homeostasis, the local RAS is predominantly related to inflammatory processes, modulating vascular permeability, apoptosis, cellular growth, migration and differentiation [ 6].

It prevents inflammatory cell infiltration, modulates vascular tone and controls smooth muscle cell proliferation [ 2- 4].

Corada, M. et al. The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.

NO modulates vascular tone and structure but the relative contributions of cGMP-dependent versus cGMP-independent mechanisms remain uncertain.

COX-2-derived prostacyclin modulates vascular remodeling.