Sentence examples for modulate tumour sensitivity from inspiring English sources

The metabolic activity confers to cancer cells the ability to inactivate cytochrome P450 3A substrates and may modulate tumour sensitivity to anticancer drugs.

The role of stromal cells and the tumor microenvironment in general in modulating tumour sensitivity is crucial to developing successful anticancer therapeutics.

Mesenchymal stem cells are, in addition to other cells in the tumour microenvironment, increasingly identified as an important population of cells that modulate tumour progression and drug sensitivity.

This study addresses the hypothesis that chronic oxidative stress can modulate tumour growth and spread by modulating surrounding tumour fibroblasts.

Fifth, TS tumour levels may be simultaneously markers of tumour aggressiveness and tumour sensitivity to 5FU.

Trastuzumab may modulate tumour microenvironment by inhibiting tumour-mediated immunosuppression via factors like PD-1 (Stagg et al, 2011).

However, tumour cells are a major source of NO production that can affect angiogenesis and modulate tumour progression.

Our findings demonstrate the ability of rationally engineered drug nanoparticle combinations to efficiently modulate tumour-associated macrophages for cancer immunotherapy.

Direct evidence for breast tumour fibroblasts modulating tamoxifen sensitivity in tumour cells has recently been reported [ 65].

As well as modulating tumour biology at the molecular level, hypoxia exerts cellular level effects on solid tumours.

Recent data suggest that recombinant human erythropoietin (rhEPO) modulates tumour growth and therapy response.