Sentence examples for modulate tumour microenvironment from inspiring English sources

Trastuzumab may modulate tumour microenvironment by inhibiting tumour-mediated immunosuppression via factors like PD-1 (Stagg et al, 2011).

RT may provide a local anti-tumour immune effect and modulate the tumour microenvironment.

These ligands could modulate the tumour microenvironment in other ways, independently of the recruitment of T cells.

Low dose ionizing radiation stimulates a localized pro-inflammatory milieu thereby modulating the tumour microenvironment.

Lack of Usp18 modulates the tumour microenvironment by upregulating Cxcr3 ligands in PyVmT MECs, particularly Cxcl10, creating aTh1-biased cytokine network.

The next part of our study therefore aimed to decipher the global involvement of known angiogenic genes in modulating the tumour microenvironment.

Thus, for some novel drugs that provide benefit without a corresponding reduction in PSA, a reduction in bone turnover markers provides additional objective evidence that the drug is modulating the tumour microenvironment in a therapeutically favourable manner.

Clinical trial of nab-paclitaxel in PDAC has shown some promise in combination with gemcitabine (Von Hoff et al, 2011), however, the full role of SPARC in modulating the tumour microenvironment is unclear, with few changes seen in tumour stroma when preclinical PDAC models were treated (Frese et al, 2012).

They can modulate tumour growth and microenvironment by mediating interactions between cancer cells and infiltrating inflammatory cells.

Therefore, it is important to study the function of Th17 cells in malignant diseases in depth and try to elucidate their mechanism of action and their modulation by tumour microenvironment to find a possibility how Th17 cells have to be modulated that they are beneficial for tumour patients.

Exosomes modulate tumor microenvironment by delivering miRNA.