Sentence examples for modulate tumor behavior from inspiring English sources

Chemokines modulate tumor behavior by three important mechanisms: regulation of tumor-associated angiogenesis, activation of a host tumor-specific immunological response, and direct stimulation of tumor cell proliferation in an autocrine fashion.

Cancer cells are able to release nano-sized vesicles, called exosomes, which modulate tumor behavior in the surrounding microenvironment.

To date, no studies have investigated the influence of MMP SNP genotype on the ability of the stromal environment to modulate tumor behavior.

Within this context, lysyl oxidase (LOX) is thought to play an important role in modulating tumor behavior.

The strong linkage between these chromatin-modulating genes and tumor behavior, along with the increasing importance of epigenetic regulation in cancer, suggest these genes may be valuable biomarkers and detection of their mutation status may aid in clinical decision making [ 23– 25].

There is increasing recognition of the importance of the microenvironment in modulating tumor cell behavior [ 1, 2, 38], particularly of the role of fibroblasts in this process [ 5, 9].

Moreover, fibroblasts activated by miR-9-5p althe tumorumor behavior, modulating genes involved in cell motility and extracellular matrix (ECM) modeling [43].

In contrast to cytotoxics, these agents modulate tumor environments and/or cellular targets and are expected to delay tumor growth.

For the TN, we analyze diverse strategies to modulate tumor hypervascularization and hypoxia, tumor extracellular matrix, and the inflammatory and tumor immunosuppressive environment.

Defects in these DNA damage responses (DDR) promote tumor initiation, drive tumor progression, and modulate tumor response to radiation, chemo, as well as immune therapies.

Exosomes modulate tumor microenvironment by delivering miRNA.